how to remove a hard drive from a Windows VM

From Server Manager, Disk Management -> offline the disk
From VMware Virtual Center, select the VM, edit settings, remove the target disk

can be done online, no downtime needed for most situations.

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How to turn off Internet Explorer Enhanced Security

Open Server Manager

If your server is running Windows ServerĀ® 2008 R2, in the Security Information section of Server Summary, click Configure IE ESC to open the Internet Explorer Enhanced Security Configuration dialog.

If your server is running Windows ServerĀ® 2012, click Configure this local server to open the Local Server configuration page. Then, in the Properties area, next to IE Enhanced Security Configuration, click On to open the Internet Explorer Enhanced Security Configuration dialog.